Molecular genetics of aminoglycoside resistance genes and familial relationships of the aminoglycoside-modifying enzymes
نویسندگان
چکیده
منابع مشابه
Molecular genetics of aminoglycoside resistance genes and familial relationships of the aminoglycoside-modifying enzymes.
The three classes of enzymes which inactivate aminoglycosides and lead to bacterial resistance are reviewed. DNA hybridization studies have shown that different genes can encode aminoglycoside-modifying enzymes with identical resistance profiles. Comparisons of the amino acid sequences of 49 aminoglycoside-modifying enzymes have revealed new insights into the evolution and relatedness of these ...
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ژورنال
عنوان ژورنال: Microbiological Reviews
سال: 1993
ISSN: 0146-0749
DOI: 10.1128/mr.57.1.138-163.1993